Executive Summary
            
                CStone Pharmaceuticals reported QQ2 2025 revenue of 24.7255 million CNY with a pronounced gross loss of 46.3950 million CNY and a continued heavy investment emphasis on R&D. The quarter delivers an EBITDA of -133.1025 million CNY and a net income of -135.0915 million CNY, resulting in a net margin of -5.46% on a reported basis. YoY comparisons show material deterioration across key profitability metrics (revenue -67.69%, gross profit -236.21%, operating income -170.60%, net income -152.73%, and EPS -138.66%), while QoQ changes are flat for the quarter (qoq 0.00%). The company maintains liquidity with a current ratio of 1.441 and cash per share of 0.536 CNY, but exhibits a relatively modest cash conversion cycle and meaningful leverage (debt ratio 0.328 and debt/equity 1.242). Cash burn is driven largely by sustained R&D outlays (R&D expense of 52.5830 million CNY) and substantial selling/general/admin expenditures (combined 39.6 million CNY in the SG&A umbrella). With no explicit quarterly forward guidance disclosed, the near-term profitability hinges on pipeline progress, potential collaboration/licensing deals, and the ability to optimize R&D spend. In this context, the QQ2 outcome underscores the structural challenge facing early-stage biotech players: continued investment ahead of material revenue generation, balanced by meaningful clinical catalysts and strategic partnerships.            
         
        
        
            Key Performance Indicators
            
                                    
                                    
                        
                        
                                                    
                                QoQ: 0.00% | YoY:-236.21%                            
                                             
                                    
                        
                        
                                                    
                                QoQ: 0.00% | YoY:-170.60%                            
                                             
                                    
                        
                        
                                                    
                                QoQ: 0.00% | YoY:-152.73%                            
                                             
                                    
                        
                        
                                                    
                                QoQ: 0.00% | YoY:-138.66%                            
                                             
                             
         
        
        
        
        
            Key Insights
            
                
                                    Revenue: 24.7255m CNY; YoY -67.69%, QoQ 0.00%
Gross Profit: -46.3950m CNY; Gross Margin -1.88% (YoY -236.21%, QoQ 0.00%)
Operating Income: -138.5780m CNY; Margin -5.60% (YoY -170.60%, QoQ 0.00%)
Net Income: -135.0915m CNY; Net Margin -5.46% (YoY -152.73%, QoQ 0.00%)
EPS: -0.10 CNY; YoY -138.66%, QoQ 0.00%
R&D Expenses: 52.5830m CNY
SG&A Expenses: 39.6000m CNY (split into General/Admin 21.5310m and Selling/Marketing 17.8270m; total 39.60m in SG&A umbrella)
Operating Expenses: 92.1830m...
                
             
         
    
    
    
        
        
            Financial Highlights
            
                Revenue: 24.7255m CNY; YoY -67.69%, QoQ 0.00%
Gross Profit: -46.3950m CNY; Gross Margin -1.88% (YoY -236.21%, QoQ 0.00%)
Operating Income: -138.5780m CNY; Margin -5.60% (YoY -170.60%, QoQ 0.00%)
Net Income: -135.0915m CNY; Net Margin -5.46% (YoY -152.73%, QoQ 0.00%)
EPS: -0.10 CNY; YoY -138.66%, QoQ 0.00%
R&D Expenses: 52.5830m CNY
SG&A Expenses: 39.6000m CNY (split into General/Admin 21.5310m and Selling/Marketing 17.8270m; total 39.60m in SG&A umbrella)
Operating Expenses: 92.1830m CNY
Current Ratio: 1.441; Quick Ratio: 1.203; Cash Ratio: 0.731
Debt Ratio: 0.328; Debt/equity: 1.242; Long-term Debt to Capitalization: 0.349; Total Debt to Capitalization: 0.554
Cash Per Share: 0.536 CNY; Price/Book: 15.91; Price/Sales: 202.68; EV Multiple: -37.15            
            
            Income Statement
            
                
                    
                    
                        | Metric | 
                        Value | 
                        YoY Change | 
                        QoQ Change | 
                    
                    
                    
                                                
                                | Revenue | 
                                24.73M | 
                                -67.69% | 
                                0.00% | 
                            
                                                    
                                | Gross Profit | 
                                -46.40M | 
                                -236.21% | 
                                0.00% | 
                            
                                                    
                                | Operating Income | 
                                -138.58M | 
                                -170.60% | 
                                0.00% | 
                            
                                                    
                                | Net Income | 
                                -135.09M | 
                                -152.73% | 
                                0.00% | 
                            
                                                    
                                | EPS | 
                                -0.10 | 
                                -138.66% | 
                                0.00% | 
                            
                                            
                
             
         
        
        
            Key Financial Ratios
            
                                    
                    
                                    
                    
                        
                            grossProfitMargin                        
                        
                            -187.6%                        
                        
                                                    
                     
                                    
                    
                        
                            operatingProfitMargin                        
                        
                            -560%                        
                        
                                                    
                     
                                    
                    
                                    
                    
                                    
                    
                                    
                    
                                    
                    
                                    
                    
                             
         
        
        
    
    
    
        
            Management Commentary
            
                No earnings call transcript highlights are available for QQ2 2025. Transcript data is not provided in the source material.            
            
            
         
        
        
            Forward Guidance
            
                There is no formal forward guidance disclosed for QQ2 2025. Given the substantial R&D spend and the current lack of near-term profitability, the key catalysts to monitor include pipeline progress across Sugemalimab and other assets (e.g., GAVRETO, avapritinib) and any upcoming regulatory or clinical milestones. Investors should watch for: (1) readouts from mid-to-late-stage trials, (2) updates on potential licensing or collaboration discussions that could monetize late-stage assets, and (3) any changes to the companyβs capital structure or liquidity runway. In the absence of explicit guidance, the assessment focuses on milestone-driven upside vs. continued burn. Near-term factors to monitor include cash runway sufficiency, potential partnerships, and any indications of operating leverage as the pipeline nears potential commercialization.