Reported Q: Q2 2025 Rev YoY: +23.2% EPS YoY: +16.5% Move: +2.78%
Twist Bioscience
TWST
$48.79 2.78%
Exchange NASDAQ Sector Healthcare Industry Medical Diagnostics Research
Q2 2025
Published: May 5, 2025

Company Status Snapshot

Fast view of the latest quarter outcome for TWST

Reported

Report Date

May 5, 2025

Quarter Q2 2025

Revenue

92.79M

YoY: +23.2%

EPS

-0.66

YoY: +16.5%

Market Move

+2.78%

Previous quarter: Q1 2025

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Earnings Highlights

  • Revenue of $92.79M up 23.2% year-over-year
  • EPS of $-0.66 increased by 16.5% from previous year
  • Gross margin of 49.6%
  • Net income of -39.33M
  • "We have spun out DNA data storage as an independent company. Atlas Data Storage will be a pure‑play company focused on end‑to‑end data storage... Twist will receive approximately 24% equity interest in Atlas on a fully diluted basis as well as royalties on future commercial sales and up to $75 million in future milestone payments, ensuring we continue to participate in future upside opportunities." - Emily Leproust, CEO & Co-Founder
TWST
Company TWST

Executive Summary

Twist Bioscience delivered a record QQ2 2025 with revenue of $92.8 million, up 23% year over year and 4.6% sequentially, and a gross margin of 49.6%, driven by higher volumes and ongoing process improvements. Despite the top-line strength, the company reported a net loss of $39.3 million and an adjusted EBITDA loss of $14.8 million for the quarter, reflecting ongoing investment in growth initiatives and the ramp in high-velocity SynBio and NGS offerings. Notably, Twist announced a strategic pivot in the form of Atlas Data Storage, a spin-out that received a $155 million equity investment from a consortium of partners. Twist will retain roughly 24% equity in Atlas on a fully diluted basis and receive up to $75 million in milestone payments plus a $2.5 million upfront cash receipt and a $2 million promissory note. Management expects gross margin to approach 50% in the back half of 2025 and reiterates 2025 revenue guidance of $372–$379 million, with adjusted EBITDA loss narrowing to a range of $48–$53 million. An accelerated path to adjusted EBITDA breakeven is targeted by the end of fiscal 2026, supported by the Atlas transaction and operating leverage from higher volumes. The company continues to pursue share gains across SynBio, NGS, and Biopharma, while expanding its academic and diagnostic offerings through initiatives such as Express Genes promotions and the Twist Wallet, aimed at broadening customer adoption. The macro environment remains mixed, with academic funding pressures contrasted by growing demand in NGS diagnostics and biotech services. Investors should monitor the pace of MRD-related deployments, the contribution from Atlas to Twist’s overall profitability, and the trajectory of gross margins as the company scales production and leverages fixed costs.

Key Performance Indicators

Revenue
Increasing
92.79M
QoQ: 4.60% | YoY: 23.23%
Gross Profit
Increasing
46.03M
49.60% margin
QoQ: 7.44% | YoY: 49.04%
Operating Income
Increasing
-41.56M
QoQ: -19.97% | YoY: 14.99%
Net Income
Increasing
-39.33M
QoQ: -24.48% | YoY: 13.55%
EPS
Increasing
-0.66
QoQ: -24.53% | YoY: 16.46%

Revenue Trend

Margin Analysis

Historical Earnings Comparison

PeriodRevenue ($M)EPS ($)YoY GrowthReport
Q2 2025 92.79 -0.66 +23.2% View
Q1 2025 88.71 -0.53 +24.1% View
Q4 2024 84.71 -0.60 +26.5% View
Q3 2024 81.46 -1.47 +27.8% View
Q2 2024 75.30 -0.79 +25.1% View